REPRODIVAC - Next-generation vaccines and diagnostics to prevent livestock reproductive diseases of worldwide impact
Objectives
Main objectives of the project are:
These objectives will be reach by exploiting recombinant systems and apply the following cutting-edge approaches:
- Reverse and structural vaccinology (‘reverse vaccinology 2.0’) to select and design both vaccine and diagnostic candidate antigens.
- Relevant protein expression systems for the production of vaccine and diagnostic candidate antigens.
- Mutagenesis and recombineering to produce rationally attenuated and viral vectored vaccines.
- Molecular and serological diagnostic approaches for DIVA and set-up of PoC tests.